The lower the aspect ratio, the middle number, the less protection you have for potholes damaging the rims. Also, the sidewall is stiffer resulting in a slightly rougher ride. The extra width can be bad with snow, but great for dry weather traction. The wider the tire, the more traction; the more traction, the lower the mpg.

There are multiple tire makers in the market place for your tire size. Go to Tirerack.com and take a look. They also have survey results to show you what others think about noise, traction in wet and snow, noise, etc.
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