possible. I guess the nut could rust/fail and the piston come out or somesuch.

Hint...use a jackstand and the car's weight to compress the springs!!

take off the wheel, put a jackstand under the strut at the ball joint and let the weight of the car compress the spring. THEN put on TWO spring compressors as near 180 apart as you can. Tighten them enough to hold and lift up the car a little.

I'd loosen the jesus nut before I took out the strut assembly (held on by the other two nuts on the strut tower) or jacked up the car (take off the link to the sway bar and strut may drop enough to swing the strut out of the wheel well and you can remove the spring. )

Your real problem will be getting the gland nut off...every one I've ever done, including those I've done before (and greased up with antiseize) I've had to remove with a pipe wrench and a couple of three foot cheater pipes. One of these days I'm probably going to have to replace a strut, either because the base has rusted off or I've chewed through the strut.