I was thinking about that once. Stuck a D-jet mani on the motor while the carbs were off once and found that it didn't fit into the tapered front end of the PV engine bay. Then there's my R-sport head, which doesn't have injector ports drilled. Then I looked at DCOE style throttle bodies, and decided that for the price the DCOE's really do work quite well enough.

I have seen injector pad drills that you can use to drill into a carb body and make an injector mount, if you are somewhat crafty you can even mostly hide the end result inside the fuel bowl. I've seen SU's converted like this in the past that had the injectors hiding in the now empty dome.

As for the current state of tune on the DCOE's - it's a case of the good being the enemy of the better. It's good enough now that I'm not wanting to start messing around with expensive sets of jets in sets of 4 to make it better. Starts in cool weather, gets lousy MPG, goes like stink, and maintains a nice 13:1 ish mixture most of the time (when not going over bumps or around corners).

Most of my tinkering these days is done on the 245. Which is megasquirted, running on E85, 16V turbo.
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'63 PV544 rat rod, '93 Classic #1141 245 +t